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Showing 1 - 50 of 89 items for (author: melcher & k)

EMDB-40983:
Negative stain EM assembly of MYC, JAZ, and NINJA complex
Method: single particle / : Zhou XE, Zhang Y, Zhou Y, He Q, Cao X, Kariapper L, Suino-Powell K, Zhu Y, Zhang F, Karsten M

PDB-8t2i:
Negative stain EM assembly of MYC, JAZ, and NINJA complex
Method: single particle / : Zhou XE, Zhang Y, Zhou Y, He Q, Cao X, Kariapper L, Suino-Powell K, Zhu Y, Zhang F, Karsten M

EMDB-29454:
Structure of Covid Spike variant deltaN135 in fully closed form
Method: single particle / : Yu X, Juraszek J, Rutten L, Bakkers MJG, Blokland S, Van den Broek NJF, Verwilligen AYW, Abeywickrema P, Vingerhoets J, Neefs J, Bakhash SAM, Roychoudhury P, Greninger A, Sharma S, Langedijk JPM

EMDB-29455:
Structure of Covid Spike variant deltaN135 with one erect RBD
Method: single particle / : Yu X, Juraszek J, Rutten L, Bakkers MJG, Blokland S, Van den Broek NJF, Verwilligen AYW, Abeywickrema P, Vingerhoets J, Neefs J, Bakhash SAM, Roychoudhury P, Greninger A, Sharma S, Langedijk JPM

EMDB-29456:
Structure of Covid Spike variant deltaN25 with one erect RBD
Method: single particle / : Yu X, Juraszek J, Rutten L, Bakkers MJG, Blokland S, Van den Broek NJF, Verwilligen AYW, Abeywickrema P, Vingerhoets J, Neefs J, Bakhash SAM, Roychoudhury P, Greninger A, Sharma S, Langedijk JPM

PDB-8fu7:
Structure of Covid Spike variant deltaN135 in fully closed form
Method: single particle / : Yu X, Juraszek J, Rutten L, Bakkers MJG, Blokland S, Van den Broek NJF, Verwilligen AYW, Abeywickrema P, Vingerhoets J, Neefs J, Bakhash SAM, Roychoudhury P, Greninger A, Sharma S, Langedijk JPM

PDB-8fu8:
Structure of Covid Spike variant deltaN135 with one erect RBD
Method: single particle / : Yu X, Juraszek J, Rutten L, Bakkers MJG, Blokland S, Van den Broek NJF, Verwilligen AYW, Abeywickrema P, Vingerhoets J, Neefs J, Bakhash SAM, Roychoudhury P, Greninger A, Sharma S, Langedijk JPM

PDB-8fu9:
Structure of Covid Spike variant deltaN25 with one erect RBD
Method: single particle / : Yu X, Juraszek J, Rutten L, Bakkers MJG, Blokland S, Van den Broek NJF, Verwilligen AYW, Abeywickrema P, Vingerhoets J, Neefs J, Bakhash SAM, Roychoudhury P, Greninger A, Sharma S, Langedijk JPM

EMDB-28907:
Gi bound mu-opioid receptor in complex with beta-endorphin
Method: single particle / : Wang Y, Zhuang Y, DiBerto JF, Zhou XE, Schmitz GP, Yuan Q, Jain MK, Liu W, Melcher K, Jiang Y, Roth BL, Xu HE

EMDB-28908:
Gi bound mu-opioid receptor in complex with endomorphin
Method: single particle / : Wang Y, Zhuang Y, DiBerto JF, Zhou XE, Schmitz GP, Yuan Q, Jain MK, Liu W, Melcher K, Jiang Y, Roth BL, Xu HE

EMDB-28909:
Gi bound delta-opioid receptor in complex with deltorphin
Method: single particle / : Wang Y, Zhuang Y, DiBerto JF, Zhou XE, Schmitz GP, Yuan Q, Jain MK, Liu W, Melcher K, Jiang Y, Roth BL, Xu HE

EMDB-28911:
Gi bound kappa-opioid receptor in complex with dynorphin
Method: single particle / : Wang Y, Zhuang Y, DiBerto JF, Zhou XE, Schmitz GP, Yuan Q, Jain MK, Liu W, Melcher K, Jiang Y, Roth BL, Xu HE

EMDB-28912:
Gi bound nociceptin receptor in complex with nociceptin peptide
Method: single particle / : Wang Y, Zhuang Y, DiBerto JF, Zhou XE, Schmitz GP, Yuan Q, Jain MK, Liu W, Melcher K, Jiang Y, Roth BL, Xu HE

PDB-8f7q:
Gi bound mu-opioid receptor in complex with beta-endorphin
Method: single particle / : Wang Y, Zhuang Y, DiBerto JF, Zhou XE, Schmitz GP, Yuan Q, Jain MK, Liu W, Melcher K, Jiang Y, Roth BL, Xu HE

PDB-8f7r:
Gi bound mu-opioid receptor in complex with endomorphin
Method: single particle / : Wang Y, Zhuang Y, DiBerto JF, Zhou XE, Schmitz GP, Yuan Q, Jain MK, Liu W, Melcher K, Jiang Y, Roth BL, Xu HE

PDB-8f7s:
Gi bound delta-opioid receptor in complex with deltorphin
Method: single particle / : Wang Y, Zhuang Y, DiBerto JF, Zhou XE, Schmitz GP, Yuan Q, Jain MK, Liu W, Melcher K, Jiang Y, Roth BL, Xu HE

PDB-8f7w:
Gi bound kappa-opioid receptor in complex with dynorphin
Method: single particle / : Wang Y, Zhuang Y, DiBerto JF, Zhou XE, Schmitz GP, Yuan Q, Jain MK, Liu W, Melcher K, Jiang Y, Roth BL, Xu HE

PDB-8f7x:
Gi bound nociceptin receptor in complex with nociceptin peptide
Method: single particle / : Wang Y, Zhuang Y, DiBerto JF, Zhou XE, Schmitz GP, Yuan Q, Jain MK, Liu W, Melcher K, Jiang Y, Roth BL, Xu HE

EMDB-28066:
Fentanyl-bound mu-opioid receptor-Gi complex
Method: single particle / : Zhuang Y, Wang Y, Guo S, Zhou XE, Rao Q, He X, He B, Liu J, Zhou Q, Wang X, Liu W, Jiang X, Yang D, Chen X, Jiang Y, Jiang H, Shen J, Melcher K, Wang M, Xie X, Xu HE

EMDB-28069:
Morphine-bound mu-opioid receptor-Gi complex
Method: single particle / : Zhuang Y, Wang Y, Guo S, Zhou XE, Rao Q, He X, He B, Liu J, Zhou Q, Wang X, Liu W, Jiang X, Yang D, Chen X, Jiang Y, Jiang H, Shen J, Melcher K, Wang M, Xie X, Xu HE

EMDB-28077:
Oliceridine-bound mu-opioid receptor-Gi complex
Method: single particle / : Zhuang Y, Wang Y, Guo S, Zhou XE, Rao Q, He X, He B, Liu J, Zhou Q, Wang X, Liu W, Jiang X, Yang D, Chen X, Jiang Y, Jiang H, Shen J, Melcher K, Wang M, Xie X, Xu HE

EMDB-28085:
SR17018-bound mu-opioid receptor-Gi complex
Method: single particle / : Zhuang Y, Wang Y, Guo S, Zhou XE, Rao Q, He X, He B, Liu J, Zhou Q, Wang X, Liu W, Jiang X, Yang D, Chen X, Jiang Y, Jiang H, Shen J, Melcher K, Wang M, Xie X, Xu HE

EMDB-28086:
PZM21-bound mu-opioid receptor-Gi complex
Method: single particle / : Zhuang Y, Wang Y, Guo S, Zhou XE, Rao Q, He X, He B, Liu J, Zhou Q, Wang X, Liu W, Jiang X, Yang D, Chen X, Jiang Y, Jiang H, Shen J, Melcher K, Wang M, Xie X, Xu HE

EMDB-28088:
DAMGO-bound mu-opioid receptor-Gi complex
Method: single particle / : Zhuang Y, Wang Y, Guo S, Zhou XE, Rao Q, He X, He B, Liu J, Zhou Q, Wang X, Liu W, Jiang X, Yang D, Chen X, Jiang Y, Jiang H, Shen J, Melcher K, Wang M, Xie X, Xu HE

PDB-8ef5:
Fentanyl-bound mu-opioid receptor-Gi complex
Method: single particle / : Zhuang Y, Wang Y, Guo S, Zhou XE, Rao Q, He X, He B, Liu J, Zhou Q, Wang X, Liu W, Jiang X, Yang D, Chen X, Jiang Y, Jiang H, Shen J, Melcher K, Wang M, Xie X, Xu HE

PDB-8ef6:
Morphine-bound mu-opioid receptor-Gi complex
Method: single particle / : Zhuang Y, Wang Y, Guo S, Zhou XE, Rao Q, He X, He B, Liu J, Zhou Q, Wang X, Liu W, Jiang X, Yang D, Chen X, Jiang Y, Jiang H, Shen J, Melcher K, Wang M, Xie X, Xu HE

PDB-8efb:
Oliceridine-bound mu-opioid receptor-Gi complex
Method: single particle / : Zhuang Y, Wang Y, Guo S, Zhou XE, Rao Q, He X, He B, Liu J, Zhou Q, Wang X, Liu W, Jiang X, Yang D, Chen X, Jiang Y, Jiang H, Shen J, Melcher K, Wang M, Xie X, Xu HE

PDB-8efl:
SR17018-bound mu-opioid receptor-Gi complex
Method: single particle / : Zhuang Y, Wang Y, Guo S, Zhou XE, Rao Q, He X, He B, Liu J, Zhou Q, Wang X, Liu W, Jiang X, Yang D, Chen X, Jiang Y, Jiang H, Shen J, Melcher K, Wang M, Xie X, Xu HE

PDB-8efo:
PZM21-bound mu-opioid receptor-Gi complex
Method: single particle / : Zhuang Y, Wang Y, Guo S, Zhou XE, Rao Q, He X, He B, Liu J, Zhou Q, Wang X, Liu W, Jiang X, Yang D, Chen X, Jiang Y, Jiang H, Shen J, Melcher K, Wang M, Xie X, Xu HE

PDB-8efq:
DAMGO-bound mu-opioid receptor-Gi complex
Method: single particle / : Zhuang Y, Wang Y, Guo S, Zhou XE, Rao Q, He X, He B, Liu J, Zhou Q, Wang X, Liu W, Jiang X, Yang D, Chen X, Jiang Y, Jiang H, Shen J, Melcher K, Wang M, Xie X, Xu HE

EMDB-26103:
Cryo-EM structure of corticotropin releasing factor receptor 2 bound to Urocortin 1 and coupled with heterotrimeric G11 protein
Method: single particle / : Zhao LH, Lin J, Mao C, Zhou XE, Ji S, Shen D, Xiao P, Melcher K, Zhang Y, Yu X, Xu HE

EMDB-26104:
Cryo-EM structure of corticotropin releasing factor receptor 2 bound to Urocortin 1 and coupled with heterotrimeric Go protein
Method: single particle / : Zhao LH, Lin J, Mao C, Zhou XE, Ji S, Shen D, Xiao P, Melcher K, Zhang Y, Yu X, Xu HE

PDB-7try:
Cryo-EM structure of corticotropin releasing factor receptor 2 bound to Urocortin 1 and coupled with heterotrimeric G11 protein
Method: single particle / : Zhao LH, Lin J, Mao C, Zhou XE, Ji S, Shen D, Xiao P, Melcher K, Zhang Y, Yu X, Xu HE

PDB-7ts0:
Cryo-EM structure of corticotropin releasing factor receptor 2 bound to Urocortin 1 and coupled with heterotrimeric Go protein
Method: single particle / : Zhao LH, Lin J, Mao C, Zhou XE, Ji S, Shen D, Xiao P, Melcher K, Zhang Y, Yu X, Xu HE

EMDB-23708:
ATP-bound AMP-activated protein kinase
Method: single particle / : Yan Y, Mukherjee S, Harikumar KG, Strutzenberg T, Zhou XE, Powell SK, Xu T, Sheldon R, Lamp J, Brunzelle JS, Radziwon K, Ellis A, Novick SJ, Vega IE, Jones R, Miller LJ, Xu HE, Griffin PR, Kossiakoff AA, Melcher K

PDB-7m74:
ATP-bound AMP-activated protein kinase
Method: single particle / : Yan Y, Mukherjee S, Harikumar KG, Strutzenberg T, Zhou XE, Powell SK, Xu T, Sheldon R, Lamp J, Brunzelle JS, Radziwon K, Ellis A, Novick SJ, Vega IE, Jones R, Miller LJ, Xu HE, Griffin PR, Kossiakoff AA, Melcher K

EMDB-22336:
Cryo-EM structure of ATP-bound fully inactive AMPK in complex with Dorsomorphin (Compound C) and Fab-nanobody
Method: single particle / : Yan Y, Murkherjee S, Zhou XE, Xu TH, Xu HE, Kossiakoff AA, Melcher K

EMDB-22337:
Cryo-EM structure of ATP-bound fully inactive AMPK in complex with Fab and nanobody
Method: single particle / : Yan Y, Murkherjee S, Zhou XE, Xu TH, Xu HE, Kossiakoff AA, Melcher K

PDB-7jhg:
Cryo-EM structure of ATP-bound fully inactive AMPK in complex with Dorsomorphin (Compound C) and Fab-nanobody
Method: single particle / : Yan Y, Murkherjee S, Zhou XE, Xu TH, Xu HE, Kossiakoff AA, Melcher K

PDB-7jhh:
Cryo-EM structure of ATP-bound fully inactive AMPK in complex with Fab and nanobody
Method: single particle / : Yan Y, Murkherjee S, Zhou XE, Xu TH, Xu HE, Kossiakoff AA, Melcher K

EMDB-30974:
Serotonin 1D (5-HT1D) receptor-Gi protein complex
Method: single particle / : Xu P, Huang S, Zhang H, Mao C, Zhou XE, Shen DD, Jiang Y, Zhang Y, Xu HE

PDB-7e32:
Serotonin 1D (5-HT1D) receptor-Gi protein complex
Method: single particle / : Xu P, Huang S, Zhang H, Mao C, Zhou XE, Shen DD, Jiang Y, Zhang Y, Xu HE

EMDB-30971:
Apo serotonin 1A (5-HT1A) receptor-Gi protein complex
Method: single particle / : Xu P, Huang S, Zhang H, Mao C, Zhou XE, Shen DD, Jiang Y, Zhang Y, Xu HE

EMDB-30972:
Serotonin-bound Serotonin 1A (5-HT1A) receptor-Gi protein complex
Method: single particle / : Xu P, Huang S, Zhang H, Mao C, Zhou XE, Shen DD, Jiang Y, Zhang Y, Xu HE

EMDB-30973:
Aripiprazole-bound serotonin 1A (5-HT1A) receptor-Gi protein complex
Method: single particle / : Xu P, Huang S, Zhang H, Mao C, Zhou XE, Shen DD, Jiang Y, Zhang Y, Xu HE

EMDB-30975:
Serotonin 1E (5-HT1E) receptor-Gi protein complex
Method: single particle / : Xu P, Huang S, Zhang H, Mao C, Zhou XE, Shen DD, Jiang Y, Zhang Y, Xu HE

PDB-7e2x:
Apo serotonin 1A (5-HT1A) receptor-Gi protein complex
Method: single particle / : Xu P, Huang S, Zhang H, Mao C, Zhou XE, Shen DD, Jiang Y, Zhang Y, Xu HE

PDB-7e2y:
Serotonin-bound Serotonin 1A (5-HT1A) receptor-Gi protein complex
Method: single particle / : Xu P, Huang S, Zhang H, Mao C, Zhou XE, Shen DD, Jiang Y, Zhang Y, Xu HE

PDB-7e2z:
Aripiprazole-bound serotonin 1A (5-HT1A) receptor-Gi protein complex
Method: single particle / : Xu P, Huang S, Zhang H, Mao C, Zhou XE, Shen DD, Jiang Y, Zhang Y, Xu HE

PDB-7e33:
Serotonin 1E (5-HT1E) receptor-Gi protein complex
Method: single particle / : Xu P, Huang S, Zhang H, Mao C, Zhou XE, Shen DD, Jiang Y, Zhang Y, Xu HE

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